Wakeley grew up in Cheshire and modelled in New York in the 1980s before opening in London. Patronage from Princess Diana helped cement her early success, and the house expanded from eveningwear into daywear, tailoring, knitwear, accessories and jewellery, with Sposa as its bridal collection. Her flagship sat on Albemarle Street in Mayfair, and the label reached more than fifty retailers across Europe, America and the Middle East.
Appointed an OBE in 2010 for services to fashion, Wakeley has won numerous honours including three British Fashion Awards, and has long co-chaired the committee for the Fashion Targets Breast Cancer appeal. The company went into administration in 2021 following the COVID-19 pandemic.