Acra studied at the American University of Beirut, graduated magna cum laude from New York's Fashion Institute of Technology in 1986, then trained at ESMOD in Paris. She started her company in 1997 as a bridal line — born from a dress made for a friend's wedding — held her first show in 1999, and expanded to eveningwear in 2003 and ready-to-wear in 2008.
Her gowns are carried by more than 150 retailers worldwide and have been worn by Beyoncé, Angelina Jolie, Taylor Swift and Jennifer Lopez; she dressed Jill Biden for the 2021 presidential inauguration. Her atelier sits in Manhattan's Garment District.