Taught to sew by his mother, Mabille was dressing family and friends and making clothes for the Lyon opera as a teenager. He enrolled at the Chambre Syndicale de la Couture Parisienne in 1995 and graduated early, then trained at Ungaro and Nina Ricci before John Galliano spotted his talent at Dior and gave him the 1997 accessories collection.
He launched his own label in 2005 with initially unisex designs, reinventing the bow tie as a common thread between menswear and womenswear — a move praised by Karl Lagerfeld and Mick Jagger. In 2008 he showed at Paris Haute Couture Fashion Week for the first time.