Born in Gassin in 1957, La Fressange began modelling at 17 and signed exclusively with Chanel in 1983, her resemblance to Coco Chanel making her Lagerfeld's muse until the two parted ways in 1989. In 1991, with backing from the luxury group Orcofi, she created her own brand and opened a boutique on Avenue Montaigne — an immediate success in France, the US and Japan.
After losing the rights to her own name in a corporate dispute, she won them back and relaunched her eponymous clothing line in 2016. Since 2013 she has also designed for Uniqlo, and in 1998 was named to the International Best Dressed List Hall of Fame.