Raised in Rome by a dressmaker mother who designed Alitalia's uniforms, Biagiotti abandoned an archaeology degree for fashion, working alongside her mother before opening her first store in Florence. In April 1988 she became the first Italian designer to present a collection in China.
The house spans women's wear, men's wear, accessories and watches, and Biagiotti was honoured by the President of Italy in 1995 and with China's Marco Polo award for promoting fashion there. Her daughter, Lavinia Biagiotti Cigna, joined the family business in 1997 and became vice president in 2005.